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PRESENTATIONS AT
THE NATIONAL AND INTERNATIONAL MEETINGS
(invited speaker, symposium speaker, podium and poster
etc.) 2007
Ray, S. D.,
Bulku, E., Zinkovsky, D., Parmar, M., Zinkovsky, D., Syed, Bulku, E., Rathod, J., Ismail, S., Parmar, M. and
Ray, S. D.
Antiapoptotic and Antinecrotic Properties of Bioflavonoids Curcumin and
Rutin. Am. J. of Pharma. Edu.
71 (3) Article 60, 2007. [AACP Annual meeting held in
Rathod,
J., Ismail, S., Parmar, M. and
Ray, S. D. Modulation of matrix metallo proteases (MMPs) and MDM2
during acute dimethylnitrosamine (DMN)-induced nephrotoxicity in mice.
The FASEB Journal.
21:730.2, 2007. [Exptl. Biology 2007 meeting held at the Ismail, S., Rathod, J., Parmar, M. and
Ray, S. D. Modulation of expression of matrix
metallo proteinases (MMPs -9, -10, & -12) during dimetyl nitrosamine
(DMN)-induced liver cell death. Society of Toxicology meetings,
Ray, S. D.,
Parmar, M., Zinkovsky, D., Syed,
S.
D. Ray.
“How Antitoxic and Anticancer signals Maneuver Programmed and Unprogrammed
Cell Death In Vivo?
Proceedings of the Apoptosis Congress,
Editor: Marc Diderich,
N. Patel and
S. D. Ray.
Silymarin pre-exposure modulates oxidative stress and bcl-xl
expression in the liver and prevents doxorubicin-induced apoptotic and
necrotic cell deaths. The Toxicologist, Vol. 90,
Abst# 1979, 2006. [Society of Toxicology meetings, E. Bulku, D. Zinkovsky, N. Patel and
S. D. Ray.
Curcumin pre-exposure in vivo prevents acetaminophen-induced
apoptotic and necrotic cell deaths in the liver.
FASEB JOURNAL 20 (5):
A1144-A1144, Part 2, Mar 7, 2006. [Experimental Biology meetings, Elida Bulku, Jasmine Rathod, Ismail Syed, Daniel Zinkovsky,
and S. D.
Ray. Exposure to
curcumin and citrus bioflavonoids prevent acetaminophen-induced programmed
and unprogrammed cell deaths in the liver. Proceedings of the
Gordon Research Conference,
Meeting held at the
2005
Ray, S. D.,
S. Stohs and G. B.. Corcoran. Activation of endonuclease, or caspase-activated
DNAse (CAD), as a marker of apoptosis rather than necrosis in drug- or
chemical-induced oncosis in vivo. The
Toxicologist, Vol. 64, Abst# 2301, 2005. Ray, S. D., A. Nagori; A. Naqvi; N. Shah, N. Patel and S. Stohs. Four week exposure to a novel nutritional mixture containing a series of polyphenolic phytochemicals antagonizes acetaminophen-induced hepatotoxicity in vivo. The Toxicologist, Vol. 64, Abst# 1410, 2005.
Ray, S. D.,
Hackman, R. M. and Stohs, S. J. Exposure
to an ephedra and caffeine containing metabolic nutrition system for 8
months does not alter organ histopathology or serum chemistry of B6C3F1
mice.
Journal of the American Coll. of
Nutrition (Proceedings
of ACN meeting,
2003). Patel, C. P., Raje, R. and
Ray, S. D. Acute ethanol pre-exposure sensitizes liver and kidneys
to furosemide-induced apoptotic and necrotic cell deaths by selectively
influencing oxidative stress and genomic DNA fragmentation in vivo.
The Toxicologist Vol. 73, S-1, 2004. Phadke, S., Patel, C. and
Ray, S. D. Liver cell death after acetaminophen (AP) overdose:
apoptosis or oncotic necrosis?
Toxicological Sciences Vol. 73, S-1, 2004. Ray, S. D., R. Hackman and S. Stohs. Exposure for one year to a metabolic nutrition system containing ephedra and caffeine does not alter serum chemistry profile or target organ histopathology of B6C3F1 mice. Toxicological Sciences Vol. 73, S-1, 2004.
Ray, S. D.
Antitoxic properties of polyphenolic phytochemicals in vivo. Symposium
Speaker, Worldnutra Congress,
Ray, S. D.
Molecular regulation of antiapoptotic and antinecrotic pathways by citrus
bioflavonoids.
AMERICAN CHEMICAL SOCIETY 228:
U71-U71 132-AGFD, Part 1, AUG 22, 2004. 2003
Ray, S. D.
Drug and Chemically Induced Free Radical-Mediated Patterns of Target Organ
Cell Death In Vivo. Proc. Soc. of Free Radical Research,
Ray, S. D.
Oxidative stress is the master operator of drug and chemically-induced
programmed and unprogrammed cell death: Implications of natural antioxidants
in vivo. Int. Congress on Food factors,
Ray, S. D.
Oxidative stress orchestrates both apoptosis & necrosis in vivo: A new
perspective from molecular toxicology.
Free Rad. Res. Vol. 37, (suppl.), pp.
29, 2003.
Ray, S. D., S. Gross, A. Chou, C. Brucculeri, D. Bagchi and Phadke, S., Raje, R. R. and Ray, S. D. Acute ethanol (EtOH) exposure in vivo potentiates acetaminophen (AAP)-induced hepatocellular apoptosis by modulating oxidative stress and expression of bcl-XL and p53 genes in the liver. The Toxicologist 72(1): 361 (#1752), 2003. [*Phadke: SOT National award winner] Stohs, S., Gross, S., Patel, C., Hackman, R. and
Ray, S. D. In vivo exposure to an
ephedra containing metabolic nutrition system does not alter serum
biochemistry and histopathology of seven vital target organs of B6C3F1 mice.
The Toxicologist 72(1): 255 (#1243), 2003. 2002 Rotollo, J. A. and Ray, S. D. Streptozotocin (STZ)-induced hyperglycemia differentially modulates acetaminophen (AAP)-induced hepatic expression of cytokine levels and apoptotic cell death. Toxicological Scs. 60(1): 377, 2002. [* J. Rotollo: SOT National award winner]
Ray, S. D. et al.
Reversal of acetaminophen
(AAP) and thioacetamide (TAM)-induced Caspase-Activated DNAse (CAD) and
oxidative stress-mediated apoptotic and necrotic liver cell deaths by
momordica charantia fruits extracts (bioflavonoids).
Toxicological Scs. 60(1): 377, 2002.
2001
Ray, S. D., Lee, H. Y., Khantsis,
Ray, S. D., Parikh, H., Ali, S. and
Bagchi, D. IH636 Grape Seed Proanthocyanidin Extract (GSPE) exposure
significantly attenuates dimethylnitrosamine-induced liver cancer and
mortality in ICR mice. Proc.
Am. Assoc.
2000
Ray, S. D.,
Balasubramanian, G., Raje, R. R., Reid, V. E., Reddy, C.S. and Bagchi, D.
Doxorubicin-induced
hepatotoxicity
may involve apoptotic cell death by modulating expression of bcl-XL and p53.
Toxicological Scs. 4(1):100 (#530), 2000.
[G. Bala received SOT National Travel Award]
Parikh, H.,
Bagchi, D. and
Ray, S. D. Effects of long term chronic
exposure of IH636 novel grape seed
proanthocyanidin extract (GSPE) on multiple target organs in mice.
The FASEB J. 14(8): A1560, 2000.
Bagchi, D.,
Hickey, E., Parikh, H. and
Ray, S. D. In
Vivo IH636 Grape Seed Proanthocyanidin Extract (GSPE) exposure inhibits
mouse liver microsomal CYP4502E1-dependent aniline hydroxylation in vitro.
Toxicological Scs. 4(1):100 (#468),
2000.
Hickey, E. J.,
Reid, V. E., Raje, R. R. and
Ray, S. D.
Diclofenac-induced nephrotoxicity may
involve oxidative stress and massive genomic DNA fragmentation in vivo.
Toxicological Scs. 4(1):118
(#556), 2000. [Hickey received SOT National Travel Award; Long Island
University Press Release]
Raje, R. R.,
Hickey, E. J., Reid, V. E. and
Ray, S. D.
Salicylic acid and chloroform-induced
nephrotoxicities may involve genomic DNA fragmentation and cell death by
apoptosis.
Toxicological Scs. 4(1):118 (#556), 2000.
Ray, S. D., Hickey,
E. and Bagchi, D. A novel Grape Seed
Proanthocyanidin Extract (GSPE) protects multiple
target organ
toxicities induced by amiodarone (Lung), dimethylnitrosamine (Spleen), CdCl2
(Kidney) and MOCAP (Brain). FASEB J. 13(4): A187, 2000.
1999
Hickey, E.,
Parikh, H., Bagchi, D. and
Ray, S. D. IH636 Grape Seed Proanthocyanidin
Extract inhibits cytochrome P450-IIE1 dependent aniline hydroxylation in
induced and uninduced rat liver microsomes.
J. Am. Coll. Nutr. 18(5): 533 (#50), 1999.
Ray, S. D., Balasubramanian, G.,
Khander, A., Reddy, C. and
Bagchi, D. Poly (ADP-Ribose)
polymerase
modulators
4-aminobenzamide (AB) and nicotinamide (NICO) protect against acetaminophen
(AAP)-induced hepatotoxicity
in mice by influencing expression of bcl-XL and p53.
Toxicological Scs. 48(1S): 91 (#425), 1999.
1998
Wong, V., Fu,
K., Kohanchi, B., Bagchi, D and
Ray, S. D. Antioxidant grape seed extract (GSPE) and a DNA repair modulator
3-aminobenzamide (3-AB) protects doxorubicin (DOX)-induced cardiotoxicity in
vivo.
Toxicological Scs. 48(1S): 156
(#731), 1998. [V. Wong: Received E.Merck/W.Virnia Univ. Undergrad Pharm.
award]
Ray, S. D., Patel, D., Wong, V., Fu,
K., Rinkovsky, A. and Bagchi, D. Effect of a novel IH636 grape seed
proanthocyanidin extract on acetaminophen-induced nephrotoxicity.
39th Annual Meeting of the
Ray, S. D., Kumar, M. A. and Bagchi,
D. In Vivo abrogation of
acetaminophen-induced hepatic genomic DNA fragmentation and apoptotic cell
death by a novel grape seed proanthocyanidin extract GSPE.
The FASEB J.
12(5), Pp. A779 #4516,
1998.
[*Above
minisymposium presentation was chosen by FASEB National Program Committee
for Press release]
Ray, S. D. Modulation of expression
of Bcl-2, Bcl-XL and Bcl-XS during acetaminophen induced hepatocellular
apoptosis,
1998.
Toxicological Scs.
42 (1S), Pp.190.
1997
Strika, S.1,
Dobrogowska, A2, Khander, A. and
Ray, S. D. Furosemide induces apoptosis in the liver and kidneys in
vivo. The Toxicological Scs. 42(1S),
Pp 357, 1997. [1&2: Received E.Merck/W.Virnia Univ. Undergrad Pharm.
award]
Ray, S. D.
Does ethanol potentiate acetaminophen-induced hepatocellular apoptosis? Fund. Appl. Toxicol. 36 (1), Pp. 247, 1997. Manolas, T., Wattamwar, A. and
Ray, S. D. Induction of hepatocellular apoptosis by
various alcohols in normal and Spontaneously Hypertensive-Stroke
Prone rats.
Fund. Appl. Toxicol. (The
Toxicologist) 36 (1), Pp. 247,
1997.
[T. Manolas received E.Merck/W.Virnia Univ. Undergrad award winner]
1996
Ray, S. D. Munoz, R., and Kraner, J. C. 3-Aminobenzamide, a
modulator of apoptosis and necrosis induced by acetaminophen does not
interfere woth p450IIE1 activity in
vivo or in vitro.
Fund. Appl. Toxicol.
30 (1), Pp. 71, 1996. Dhruva, D., Sharma, S., Shleyfer, L., Raje, R. R. and
Ray, S. D. Acetaminophen induced hepatocellular apoptosis
in vivo: Role of Ca2+ -activated
nitric oxide pathway in the absence of
bcl-2 expression. Fund. Appl. Toxicol. 30 (1), Pp. 165,
1996. [Dhruva
: SOT Travel Award winner] Dhruva, D. and
Ray, S. D. Role of nitric oxide in acetaminophen-induced apoptosis and
necrosis and its modulation by 3-aminobenzamide.
J. Clinical Toxicology
34(5), Pp 575, 1996. [*Above work received
American Tran, M., Stohs, S., Newton, S., Bagchi, D., Tang, L. and
Ray, S. D. Cadmium and chromium
induced oxidative stress and programmed cell death in cultured J774A.1
macrophage cells. Fund. Appl.
Toxicol. 30 (1), Pp. 167, 1995.
1995
Ray, S. D.
and R. R. Raje.
Acetaminophen-induced hepatocellular apoptosis
in vivo shows signs of loss
of mitochondrial volume regulation.
Fund. Appl. Toxicol. (The Toxicologist) 15 (1): Pp. 133,
1995. *Yahya, S. M.,
Ray, S. D. and Raje, R. R. Abrogation of acetaminophen induced hepato- and
nephrotoxicity by 3-aminobenzamide, A DNA repair modulator.
Fund. Appl. Toxicol. (The
Toxicologist) 15 (1): Pp. 133, 1995. [*SOT Award winner]
1994
Ray, S. D.,
Mumaw, V.R., Lippman, R., Fraiss, M.W.
Acetaminophen-induced apoptosis and necrosis:
In Vivo protection by cholesteryl hemisuccinate pretreatment.
The Toxicologist
15 (1), Pp.
187, 1994. Mumaw, V.R., Ray, S. D., and Corcoran, G.B. Dimethylnitrosamine-induced DNA fragmentation and | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
