Publications
Reviews and Book Chapters:
1. Ray, S. D. and Corcoran, G. B. "Apoptosis and Cell Death" in Bryan Ballantyne’s 3rd Editionof ‘General and Applied Toxicology’, Pp. 248-312, [ISBN# 978-0-470-72327-2], JONH WYLIE Publishing, UK, Dec 2009.
2. Ray SD, Zinkovsky D, Bulku E and Patil BS. "Prevention of Drug-Induced Programmed and Unprogrammed Cell Death by Citrus Flavonoids." Potential Health Benefits of Citrus, Eds. Bhimanagouda S. Patil, Nancy D. Turner, Edward G. Miller and Jennifer S. Brodbelt. Washington DC, American Chemical Society, Pp. 144-160 (ISBN13: 9780841239579/ ISBN10: 0841239576), 2006.
3. Principal author of the Review Chapters "APOPTOSIS" in ‘Encyclopedia of Toxicology’, Ed. Philip Wexler, 2nd Eds, Vol-I, Pp. 153-178, Elsevier Science Publishing. Also the Principal author of the review article on "Dimethylnitrosamine" in ‘Encyclopedia of Toxicology’, 2005.
4. Principal author of "Apoptosis and Cell Death", Vol. I, Chapter-9, Pp. 175-213, in Bryan Ballantyne’s 2nd Edition of ‘General and Applied Toxicology’, McMillan Publishing, 1999.
5. Ray, S. D. et. al. Roles of Polyphenols, Flavonoids, and Oligomeric Proanthocyanidins in Cancer Chemoprevention’ in ‘Phytopharmaceuticals in cancer chemoprevention’, Eds. H. G. Preuss and D. Bagchi, CRC Press, Pp. 311-348, [ISBN#08493-1560-3], 2005.
6. Ray, S.D. and Corcoran, G.B. Damage to the nucleus and acute cell death produced by alkylating hepatotoxins. In “Molecular Theories of Cell Life and Death”, S.Ji. Ed., Rutgers Univ. Press, NJ. Chapter -10, Pp. 384 – 400, 1991. (Times Cited-55) (Citation for the following data obtained through Scopus, SCI & Google Scholar)
7. Bulku E, Zinkovsky D, Patel P, Javia V, Lahoti T, Khodos I, Stohs SJ and Ray SD. A novel dietary supplement containing multiple phytochemicals and vitamins elevates hepatorenal and cardiac antioxidant enzymes in the absence of significant serum chemistry and genomic changes. Oxid. Med. & Cellu. Longev. (In-press, Jan 2010).
8. Patel N, Joseph C, Corcoran GB and Ray SD. Silymarin Modulates Doxorubicin-Induced Oxidative Stress, Bcl-XL and p53 Expression while Preventing Apoptotic and Necrotic Cell Death in the Liver. Toxicol. Appl. Pharmacol. (In-press,2010).
9. *Yung E, MD; Yarmush JM; Weinberg J, MD; Schianodicola, JJ, MD; and Ray SD, Ph.D. Comparison of the Potency of Lidocaine and Chloroprocaine in Sciatic Nerve Block in Sprague-Dawley Rats. Pharmacology 83(6):356-359, 2009. [*NY Methodist Hospital Collaboration, Brooklyn, NY]
10.*Yung E, MD; Lahoti T, MS; Soheila J, MD; Weinberg J, MD; Yarmush J, MD; Schianodicola, JJ, MD; and Ray SD, Ph.D. Bicarbonate Plus Epinephrine Shortens the Onset and Prolongs the Duration of Sciatic Block Using Chloroprocaine Followed by Bupivacaine in Sprague-Dawley Rats. Regional Anesthesia and Pain Medicine, 34(3): 196 – 200, 2009. [*NY Methodist Hospital Collaboration, Brooklyn, NY]
12. Ray SD, Parmar M, Rathod J, Ismail S, Zinkovsky D, Bulku E, Gigliotti J, Hackman RM and Stohs S J. Long Term Exposure Effect of a Unique Metabolic Nutrition System Containing a Diverse Group Of Phytochemicals on Serum Chemistry and Genomic and Non-Genomic Changes in the Liver of Female B6C3F1 Mice. Phytotherapy Research 22(4): 458-471, 2008.
13. Ray SD, Patel N, Nagori A, Naqvi A and Stohs SJ. Four week exposure to a novel nutritional mixture containing a series of polyphenolic phytochemicals antagonizes acetaminophen-induced programmed and unprogrammed cell death in the liver in vivo. Molecular and Cellular Biochemistry. 293(1-2):119-36, 2006. (Times cited-10)
14. Ray S, Phadke S, Patel C, Hackman RM, Stohs S. Short-term and long-term in vivo exposure to an ephedra- and caffeine-containing metabolic nutrition system does not induce cardiotoxicity in B6C3F1 mice. Archives of Toxicol. 79(6): 330-340, 2005. (Times cited-8) 9. Ray SD, Parikh H and Bagchi D. Long-Term grape seed proanthocyanidin extract exposure to B6C3F1 mice significantly attenuates dimethylnitrosamine-induced liver tumor induction and mortality by differentially modulating programmed and unprogrammed cell deaths. Mutation Research 579 (1-2): 81-106, 2005. (Times cited-15)
15. Ray, SD et al. Oxidative Stress is the Master Operator of Drug & Chemically-Induced Programmed & Unprogrammed Cell Death: Implications of Natural Antioxidants In Vivo. Biofactors, 21(1-4):223-232, 2004. (Times cited-15)
16. Ray SD. Oxidative stress orchestrates both apoptosis & necrosis in vivo: A new perspective from molecular toxicology. Proc. Of the Meeting of the Soc. Free Rad. Res, Ed. D. Galaris, Pp. 45-53, 2004. (Times cited-10)
17(a). Bagchi D, Sen CK, Ray SD, Das DK, Bagchi M, Preuss HG and Vinson JA. Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract. Mutatation Research 523-524:87-97, 2003. (Times cited: 145)
18. Bagchi D, Ray SD, Bagchi M, Preuss HG, and Stohs, SJ. Mechanistic pathways of antioxidant cytoprotection by a novel IH636 grape seed proanthocyanidin extract. Indian J. Exp. Biol. 40(6):717-726, 2002. (Times cited-15)
19. Bagchi D, Bagchi M, Stohs SJ, Ray SD, Sen CK and Preuss HG. Cellular protection with proanthocyanidins derived from grape seeds. Ann New York Acad Sciences 957:260-70; 2002. (Times cited: 110)
20. Ray SD, Balasubramanian G, Reddy CS and Bagchi D. Ca2+-Calmodulin Antagonist Chlorpromazine and Poly (ADP-Ribose) Polymerase Modulators 4-Aminobenzamide and Nicotinamide Influence Hepatic Expression of Bcl-XL and P53 and Protect against acetaminophen-induced programmed and unprogrammed cell death in mice. Free Radical Biology & Medicine, 31(3): 277-291, 2001. (Times cited: 35)
21. Hickey EJ, Raje RR, Reid VE, Gross SM, and Ray SD Diclofenac-Induced in vivo nephrotoxicity may involve oxidative stress mediated massive genomic DNA fragmentation and apoptotic cell death. Free Radical Biology & Medicine, 31(2): 139-152, 2001. (Times cited: 48)
22. Ray SD, Parikh H, Hickey E, Bagchi M, and Bagchi D. Differential effects of IH636 grape seed proanthocyanidin extract and a DNA repair modulator 4-aminobenzamide on liver microsomal CYP-4502E1 dependent aniline hydroxylation. Molecular & Cellular Biochemistry, 218: 27-33, 2001. (Times cited: 18)
23. Bagchi M, Balmoori J, Ye X, Ray SD and Stohs SJ. Protective effect of melatonin on naphthalene-induced oxidative stress and DNA damage in cultures macrophage J774A.1 cells. Molecular & Cellular Biochemistry, 221: 49-55, 2001. (Times cited-15)
24. Ray S, Bagchi D, Lim PM, Bagchi M, Gross SM, Kothari SC, Preuss HG, Stohs SJ. Acute and long-term safety evaluation of a novel IH636 grape seed proanthocyanidin extract. Res Commun Mol Pathol Pharmacol., 109(3- 4):165-97, 2001. (Times cited-40)
25. Ray, S. D. and Jena, N. A hepatotoxic dose of acetaminophen modulates expression of bcl-2, bcl-XL, and bcl-Xs during apoptotic and necrotic death of mouse liver cells in vivo. Archives of Toxicology, 73: 594-606, 2000. (Times cited: 55)
26. Ray, S. D., Patel, D., Wong, V., Rinkovsky, A., Bagchi, M., Raje, R. R. and Bagchi, D. Unique organoprotective properties of a novel a novel IH636 grape seed proanthocyanidin extract on cadmium chloride-induced nephrotoxicity, dimethylnitrosamine-induced spleenotoxicity, and mocap-induced neurotoxicity in mice. Res. Commu. Mol. Pathol. & Pharmacol., 107: 105-128, 2000. (Times cited-10)
27. Ray, S. D., Patel, D., Wong, V. and Bagchi, D. In vivo protection of DNA damage associated apoptotic and necrotic cell deaths during acetaminophen-induced nephrotoxicity, amiodarone-induced lung toxicity and doxorubicin-induced cardiotoxicity by a novel IH636 grape seed proanthocyanidin extract. Res. Commu. Mol. Pathol. & Pharmacol., 107: 137-166, 2000. (Times cited: 32)
28. Bagchi, D., Ray, S. D., Patel, D. and Bagchi, M. Protection against drug- and chemically-induced multiorgan toxicity by a novel IH636 grape seed proanthocyanidin extract. Drugs Exptl. Clin. Res., 27: 3-15, 2000. (Times cited: 30)
29. Bagchi, D ., Bagchi, M., Stohs, S., Das, D. K., Ray, S. D., Kuszynski, C. A., Joshi, S. and Preuss, H. G. Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention. Toxicology 148: 187-197, 2000. (Times cited: 380)
30. Ray, S.D., Kumar, A. and Bagchi, D. A novel proanthocyanidin IH636 extract increases in vivo bcl-XL expression and prevents acetaminophen-induced programmed and unprogrammed cell death in mouse liver. Arch. Biochem. Biophys., 369: 42-58, 1999. (Times cited: 58)
31. Babar, A., Ray, S. D., Patel, N. K., Plakoginnis, F. M. and Goginani, P. In Vitro release and diffusion studies of promethazine-HCl from polymeric dermatological bases using cellular membrane and hairless mouse skin. Drug Deliv. & Ind. Pharam., 25:235-240, 1999.
32. Bagchi, M., Balmoori, J., Bagchi, D., Ray, S. D., Kuszynski, C. and Stohs, S. J. Smokeless tobacco, oxidative stress, apoptosis, and antioxidants in human oral keratinocytes. Free Radi. Biol. and Med., 26:992-1000, 1999. (Times cited: 60)
33. Bagchi, D., Vuchetich, P. J., Bagchi, M., Tran, M. X., Krohn, R. L., Ray, S. D. and Stohs, S. J. Protective effects of Zinc salts on TPA-induced hepatic and brain lipid peroxidation, glutathione depletion, DNA damage, and peritoneal macrophage activation in mice. General Pharmacology, 30: 43-50, 1998. (Times cited: 45)
34. Bagchi, D., Tran, M. X., Newton, S., Bagchi, M., Ray, S. D., Kuszynski, C. A. and Stohs, S. J. Chromium and cadmium induced oxidative stress and apoptosis in cultured J774.1 macrophage cells. In Vitro and Molecular Toxicology, 11: 171-181, 1998. (Times cited: 10)
35. Bagchi, D., Carryl, O. R., Tran, M. X., Bagchi, M., Vuchetich, P. J., Krohn, R. L., Ray, S. D. and Stohs, S. J. Protection against chemically-induced oxidative gastrointestinal tissue injury in rats by bismuth salts. Digestive Diseases Sciences, 42: 1890-1900, 1997. (Times cited: 15)
36. Fariss, M. W., Lippman, H. R., Mumaw, V. R. and Ray, S. D. Cholesteryl hemisuccinate treatment protects rodents from the toxic effects of acetaminophen, adriamycin, carbontetrachloride, chloroform and galactosamine. Toxicology Letters, 90: 133-144, 1997. (Times cited-5)
37. Ray, S. D., Mumaw, V. R., Raje, R. R. and Fariss, M. W. Protection of acetaminophen-induced hepatocellular apoptosis and necrosis by cholesteryl hemisuccinate pretreatments. J. Pharm. Exp. Thera. 279: 1470-1483, 1996. (Times cited: 95)
38. Ray, S. D. and Fariss, M. W. Role of Cellular Energy status in tocopheryl hemisuccinate cytoprotection against Ethyl methane sulfonate-induced toxicity. Archives of Biochem. and Biophys., 311: 180-190, 1994. (Times cited: 35)
39. Fariss, M., Jhonson, S., Walton, L. P., Mumaw, V. and Ray, S. D. Tetrahydroaminoacridine-induced ribosomal changes and inhibition of protein synthesis in rat hepatocyte suspensions. Hepatology 20:240 – 246, 1994. (Times cited: 14)
40. Ray, S. D., Kamendulis,L, Gurule, M, Yorkin, R. and Corcoran, G.B. Ca2+ antagonists inhibit DNA fragmentation and toxic cell death induced by acetaminophen. FASEB Journal, Vol 7: 453-463. 1993. (Times cited: 156)
41. Kraner, J.C., Lasker, J., Corcoran, G.B., Ray, S. D. and Raucy, J.L. Elevation of P-450IIE1 by acetone in isolated rabbit hepatocytes may involve de novo m-RNA synthesis. Biochem. Pharmacol. 45 : 1483-1492, 1993. (Times cited: 25)
42. Burchiel, S.W., Davis, D., Ray, S. D. and Barton, S. DMBA induces programmed cell death (Apoptosis) in the A20.1 murine B-cell lymphoma. Fund. Appl. Toxicol. 21: 120-124, 1993. (Times cited-45)
43. Corcoran, G.B. and Ray, S. D. The role of the nucleus and other hepatocellular compartments in acute cell death produced by alkylating hepatotoxins: Contemporary Issues In Toxicology. Toxicol. Appl. Pharm. 113: 167-183, 1992. (Times cited: 55)
44. Ray, S.D., Sorge, C.L., Kamendulis, L. and Corcoran, G.B. Role of Ca2+-activated DNA fragmentation in DMN-induced hepatic necrosis: Effects of Ca2+ -endonuclease and poly (ADP-Ribose) polymerase inhibitors in mice. J. Pharmacol. Exp. Therapeu. 263: 387 – 394, 1992. (Times cited: 45)
45. Shen, W., Kamendulis, L., Ray, S. D. and Corcoran, G.B. Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: Effects of endonuclease, DNA repair and glutathione depletion inhibitors on DNA fragmentation and cell death. Toxicol. Appl. Pharmacol., 112: 32 – 40, 1992. (Times cited: 64)
46. Burchiel, S.W., Davies, D., Ray, S. D., Thilsted, J.P. and Corcoran, G.B. DMBA-induced cytotoxicity in lymphoid and non lymphoid organs of B6C3F1 mice: Relation to cell death to intracellular calcium and DNA damage. Toxicol. Appl. Pharmacol., 113:126-132, 1992. (Times cited: 25)
47. Ray, S. D., Sorge, C.L., Tavacoli, A., Raucy, J.L. and Corcoran, G.B. Extensive alteration of genomic DNA and rise in nuclear Ca2+ in vivo early after hepatotoxic acetaminophen overdose in mice. In Biological Reactive Intermediates IV. Molecular & Cellular Effects and their impact on Human Health. Adv. Exp. Med. Biol., 238: 699 – 705, 1991. (Times cited: 15)
48. Shen, W., Kamendulis, L., Ray, S. D. and Corcoran, G.B. Acetaminophen-induced cytotoxicity in cultured mouse hepatocytes: Correlation of nuclear Ca2+ accumulation and DNA fragmentation cell death. Toxicol. Appl. Pharmacol., 111: 242-254, 1991. (Times cited: 63)
49. Mehendale, H.M., Ray, S. D. and Cai, Z. Paradoxical toxicity of CCl4 in isolated hepatocytes from chlordecone, phenobarbital and mirex treated rats. In Vitro Toxicol. 4: 187 – 196, 1991. (Times cited: 5)
50. Ray, S. D., Sorge, C.L., Raucy, J.L. and Corcoran, G.B. Early loss of large genomic DNA in vivo with accumulation of Ca2+ in the nucleus during acetaminophen induced liver injury. Tox. Appl. Pharm. 106: 346 – 51, 1990. (Times cited: 52)
51. Ray, S. D. and Mehendale, H. M. Potentiation of CCl4 and CHCl3 hepatotoxicity and lethality by various alcohols. Fundam. Appl. Toxicol. 15: 429 – 440, 1990. (Times cited: 24)
52. Mehendale, H.M. and Ray, S.D. Inhibition of cell division in hepatoma cell cultures by chlordecone and carbon tetrachloride combination. Toxicology in Vitro, 4: 179 -183, 1990. (Times cited: 19)
53 .Esterline, R., Ray, S. D. and Ji, S. Reversible and Irreversible inhibition of hepatic mitochondrial respiration by acetaminophen and its toxic metabolite, N-acetyl-p-benzoquinoneimine (NAPQI). Biochemical. Pharmacol. 38: 2387-2390, 1989. (Times cited: 41)
54. Ji, S., Ray, S. D. and Esterline, R. Intracellular Dissipative Structures (IDS) as ultimate targets of chemical cytotoxicity. pp. 871-889 In Biological Reactive Intermediates III. Adv. Exp. Med. Biol. 197: 871- 889, 1986. (Times cited: 5)
55. Ray, S. D. Part-I: GA, ABA, Phenol Interaction in the control of growth: Phenolic compounds as effective modulators of GA-ABA interaction in radish seedlings. Biologia Plantarum (Checzk) 28: 361- 369, 1986. (Times cited: 13)
56. Ray, S. D. and Laloraya, M. M. Interaction of gibberellic acid, abscisic acid, and phenolic compounds in the control hypocotyl growth of Amaranthus caudatus seedlings. Canadian J. Bot.., 62: 2047- 2052, 1984. (Times cited: 12)
57. Pawar, M.S., Ray, S. D. and Laloraya, M.M. Antagonistic action of phenolic compounds on abscisic acid-induced inhibition of seed germination. Beitr. Biol. Pflanzen. (W. Germany) 60: 15 – 21, 1984. (Times cited: 12)
58. Ray, S. D., Guru, K.N. and Laloraya, M.M. Reversal of abscisic acid-induced betacyanin systhesis by phenolic compounds in Amaranthus caudatus seedlings. Physiol. Plant. (Copenhagen) 58: 175 – 178, 1983. (Times cited: 12)
59. Ray, S. D., Guru, K.N. and Laloraya, M.M. Antagonistic action of phenolic compounds on Abscisic acid induced inhibition of hypocotyl growth. J. Exp. Bot. (London) 31(125):1651- 1656, 1980. (Times cited: 18)
60. Pal, S., Arora, B., Chhutani, P.N., Choudury, S. and Ray, S. D. Rabies virus infection in a flying fox bat, Pteropus poliocephalus. Tropical & Geographic Medicine (US) 32: 265 -267, 1980. (Times cited: 10)
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