GRADUATE – THESIS SUPERVISION
Ms. Ami Patel, BPharm, MS. Aliphatic alcohols may produce nephrotoxicity via oxidative stress (OS) and influence sirt1 and FOXO3a expression in vivo. Thesis data presented at the 2012 AACP meetings and 2012 SOT meetings. Visit Pg. 256; Abst#1190.[Currently a researcher at Mt. Sinai Med Ctr, NY; formerly at the Cold Spring Harbor Laboratories, LI, NY]
Biological Scs Section- 3rd absT from top-down:http://www.ajpe.org/doi/full/10.5688/ajpe76599 http://www.toxicology.org/pubs/docs/Tox/2012Tox.pdf http://www.toxicology.org/pubs/docs/Tox/2013Tox.pdf
Mr. Vivek Lawana, BPharm, MS. Aliphatic alcohols propagate oxidative stress-responsive cell death signals in the mouse liver and kidneys by perturbing expression of pro- and anti-apoptotic genes. [Completing PhD at the Iowa State University, Ames, Iowa] http://www.fasebj.org/doi/abs/10.1096/fasebj.26.1_supplement.1050.11
Ms. Sonia D. Pravasi, BPharm, MS. Ethanol exposure potentiates diclofenac-induced nephrotoxicity in vivo. 2011 SOT travel award winner. [Currently a Sr. Scientist at Bristol Meyers Squibb, NJ]http://www.toxicology.org/pubs/docs/Tox/2011Tox.pdf
Ms. Shruti Desai, BPharm, MS. Role of Nrf2 and ARE family during ethanol-induced oxidative modulation of diclofenac-induced hepato- and nephrotoxicity. [2011 ASPETs Toxicology divisions best poster award contestant; Worked at NIMHS; currently at Oklahoma Res Foundation] http://www.fasebj.org/doi/abs/10.1096/fasebj.25.1_supplement.1087.10
Ms. Priyanka Patel, BPharm, MS. Apoptogenic, necrogenic and varied patho-morphological changes associated with diverse hepatotoxins. [Currently employed at Memorial Sloan Kettring, NY] http://www.toxicology.org/pubs/docs/Tox/2013Tox.pdf
Mr. Tejas Lahoti, BParm, MS. Acute doxorubicin-induced in vivo nephrotoxicity is associated with massive oxidative stress and an organized perturbation of mitochondria-centric pro- and anti-apoptotic genes.[ 2010 SOT travel award winner. Graduated from PennState Univ; Currently a Sr. Scientist at Celgene Corp,, CA] http://www.ncbi.nlm.nih.gov/pubmed/22873725
Ms. Arun Venkatesh, BPharm, MS –Biodistribution and bioavailability of structurally and functionally diverse antitoxic and anticancer bioflavonoids in vivo. Graduated from Louisiana State University, LA, Free Radical Biology Laboratory. GRC graduate student award winner.
Ms. Amritaparna Sengupta, BPharm, MS – Modulation of CYP3A activity by dexamethasone and grape seed proanthocyanidin extract and their combinations in rat liver in vivo. [Worked as scientist at Regeneron laboratory in NJ; Currenly at Abbevie; Gordon Conference Award winner- graduate student award winner.] http://www.fasebj.org/doi/10.1096/fasebj.22.1_supplement.1137.3
Mr. Chirag Patel, BPharm, MS – Differential expression of pro- and anti-apoptotic genes under the influence of oxidative stress during carbon tetrachloride -mediated liver injury in mice. Earned PhD at the UMDNJ, NJ; immunotoxicology laboratories; currently at Pharmaceutical industry in NJ. [2008 ASPETs Toxicology divisions best poster award contestant] http://www.fasebj.org/doi/10.1096/fasebj.22.1_supplement.1140.3
Ms. Inna Khodos, BS, MS -Exposure to a proanthocyanidin mixture alongwith dimethylnitrosamine reduces nephrocarcinogenesis in male B6C3F1 mice. Currently a scientist/toxicologist at Memorial Sloan Kettring, NY. https://www.linkedin.com/in/inna-khodos-70096618
Ms. Shruti Bhatt, B.Pharm., MS, PhD. -Modulation of pro- and anti-apoptotic genes and cell cycle regulatory elements during diclofenac-induced nephrotoxicity in female ICR mice. [Graduated from University of Miamis Miller School of Medicines oncology/cell signaling laboratory; Currently at Harvard University] [2011 ASPETs Toxicology divisions best poster award] http://www.fasebj.org/doi/10.1096/fasebj.22.1_supplement.917.9
Ms. Elida Bulku, BS, MS, Pharm.D. -Modulation of pro- and anti-apoptotic genes and cell cycle regulatory elements by curcumin during acetaminophen-induced hepatotoxicity in mice. Currently a director of Pharmacy. GRC graduate student award winner. http://www.fasebj.org/doi/10.1096/fasebj.20.5.A1144-a http://www.ingentaconnect.com/content/ben/cnr/2012/00000009/00000001/art00008
Ms. Jigna Parekh, B.Pharm., MS – Effects of structurally and functionally diverse group of phytochemicals on aniline hydroxylation (CYP2E1) of control and acetone-induced rat liver microsomes. Currently a scientist/toxicologist at Roche Laboartories; GRC award winner and ASPET’s best poster contestant. http://www.fasebj.org/doi/10.1096/fasebj.22.1_supplement.1137.3
Mr. Mayur Parmar, B.Pharm., MS -Alteration of pro- and anti-apoptotic genes and cell cycle regulatory elements during streptozotoccin-induced diabetes and oxidative stress in the liver. Finished doctoral studies in neurotoxicology at the Duquesne University, Pittsburg; Completed post-doctoral work at Weil Cornell, NY and Univ of Florida. https://scholar.google.com/citations?user=Ju3AfZgAAAAJ&hl=en
Mr. Syed Ismail, B.Pharm., MS – Modulation of expression of matrix metallo proteinases (MMPs -9, -10, & -12) during dimetylnitrosamine (DMN)-induced liver cell death. Finished PhD in toxicology at the Wayne State Univ; Now a Scientist at the Harvard University, Boston, MA. GRC graduate student award winner. https://scholar.google.com/citations?user=LmRoRlgAAAAJ&hl=en
Ms. Jasmine Rathod, B.Pharm. – Modulation of matrix metallo proteases (MMPs) and MDM2 during acute dimethylnitrosamine (DMN)-induced nephrotoxicity in mice. Currently a scientist/toxicologist at NJ environmental toxicology Laboartories. [2011 ASPET’s Toxicology division’s best poster award contestant]
Mr. Nirav Patel, B.Pharm., MS. -Role of oxidative stress and caspases during Doxorubicin-Induced organ toxicites in male ICR mice. Gordon Research Conference Graduate student Award Winner: 2005. Completed PhD at UMDNJs immuno-toxicology laboratories, Newark, NJ. https://www.sciencedirect.com/science/article/pii/S0041008X10000451 https://www.ncbi.nlm.nih.gov/pubmed/20144634
Mr. Chintan Patel, R. Ph.-Potentiation of Furosemide-induced liver injury by Ethanol in male ICR mice. SOT Natl. level graduate student travel award winner, 2004; The Toxicologist 78(S-1): Pp.400, Abst# 1942. Currently a director of Pharmacy; Regulatory pharmacist. http://www.toxicology.org/pubs/docs/Tox/2004Tox.pdf https://www.ncbi.nlm.nih.gov/pubmed/15630201
Mr. Santosh Phadke, MS, R. Ph. -Modulation of Ethanol-Potentiated Acetaminophen-induced apoptotic and necrotic death of liver cells in mouse liver”. The Toxicologist,Pp.361, Abst# 1752, 2003. SOT’’s National level graduate student travel award winner; Gordon Research Conference Graduate student Award Winner: Cancer Chemotherapy” 2001; Currently a district director of Pharmacy. http://www.toxicology.org/pubs/docs/Tox/2003Tox.pdf https://www.ncbi.nlm.nih.gov/pubmed/15630201
Mr. Jimmy Rotolo, BS, MS, Ph.D. -Modulation of Acetaminophen-induced apoptotic and necrotic death of liver cells in Streptozotocin-induced diabetic mouse liver”. The Toxicologist,66(S-1): Pp.119, Abst# 581, 2002. Gordon Research Conference Graduate student Award Winner for presenting research on “Free Radical Reactions”, New Hampshire/ SOT: 2002-Travel award winner] Completed PhD in hematology/oncology at the Cornell university, Currently a VP of R&D of a Biotechnology company at NY. https://www.ncbi.nlm.nih.gov/pubmed/15630201 http://www.toxicology.org/pubs/docs/Tox/2002Tox.pdf
Mr. Saleem Mohammad, MS, R. Ph. -Modulation of Diclofenac-induced apoptotic and necrotic death of cells in Streptozotocin-induced diabetic mouse kidneys. The Toxicologist,60(S-1): Pp.78, Abst# 377, 2001. [Gordon Conference Graduate student Award Winner: “Experimental and Clinical Cancer Chemotherapy” held at New Hampshire; Associate Professor of Pharmacy at Medical College in Pakistan. http://www.toxicology.org/pubs/docs/Tox/2001Tox.pdf
Mr. Hemal Parikh, MS, R.Ph. -Effect of Long-Term Exposure of Grape Seed Extract on Dimethylnitrosamine-Induced Liver Cancer. Presented research at the American Assoc. for Can. Res., San Francisco, CA. Currently a district director of Pharmacy at Indianapolis, IN. ASPET’s best poster award contestant. https://www.ncbi.nlm.nih.gov/pubmed/16197968 https://www.sciencedirect.com/science/article/pii/S0027510705002538
Mr. Eamon Hickey, BS, MS. -Diclofenac, Salicylic Acid and Chloroform-Induced nephrotoxicity: Apoptotic cell Death in Kidneys. [Recipient of Society of Toxicology’s Natl. level graduate student travel award, 2000] Currently a toxicologist/chemist in Ireland. SOT travel award winner.
Mr. D. Dhruva, MS, R.Ph. -Acetaminophen-induced apoptotic and necrotic cell death: Role nitric oxide. Am. Acad. Clin. Toxicol’s fellowship holder-1996] Currently a district director of Pharmacy at Seattle, WA. SOT travel award winner. J Toxicol Clin Toxicol, 1996 & The Toxicologist,30(#1; Pt.2): Pp.65, Abst# 845, 1996. http://www.toxicology.org/pubs/docs/Tox/1996Tox.pdf
Mr. Shah M. Yahya, MS, R.Ph. -Protection of acetaminophen-induced DNA fragmentation and hepatocellular death by Poly (ADP-Ribose) polymerase inhibitors. The Toxicologist,15(#1): Pp.133, Abst# 708, 1997. [Recipient of Society of Toxicology’s National level graduate student travel award 1995, and Arthur Sackler fellow, Long Island University] Currently a district director of Pharmacy at MD. SOT travel award winner.] http://www.toxicology.org/pubs/docs/Tox/1995Tox.pdf
GRADUATE THESIS COMMITTEE MEMBER AND SPECIAL RESEARCH PROJECT SUPERVISION
1) S. Sharma, R.Ph.: Modulation of apoptosis & necrosis by various alcohols in liver in vivo-1997.
2) Dr. Rafael Munoz, R.Ph.: Effects of 3-aminobenzamide in CYP450 mediated drug metabolism-1997.
3) Pardhiva, MS: Member of research committee (In Vitro Skin permeabilization of drugs)-1998.
4) Karim Aisa, R.Ph.: Member of research committee (Effect of Enarapril on SHR-SD-rats)-1998.
5) Dhiren Patel, R.Ph., PharmD.: Protection of acetaminophen-induced nephrotoxicity by grape seed extract-1999.
6) Joan Simonneli, MS: Member of thesis committee (m-RNA expression by Quercetin & Resveratrol)-1999.
7) Biren Amin, R.Ph.: Member of thesis committee. (m-RNA expression by Diadzin and Naringenin)-2000.
8) Yasir Naroo, R.Ph.: Member of thesis committee (m-RNA expression by Genistin)-2000.
9) Daniella Weng, R.Ph., MS: Member thesis committee.(Pharmacokinetics/Iontophoresis of Zidovudine)-2001.
10) Dr. Migumi Tonegawa, MD (Japan): Member of her thesis committee (PKC expression)-2001.
11) Gary Wang, R.Ph., PharmD.: Member of his thesis committee (PKC expression)-2002.
12) Ketan Thakkar, R.Ph., MS: Drug and Chemically-induced programmed cell death in spleen.
13) Dr. Shuvendu Sen, MD: Histopathological diagnosis of apoptosis in drug-exposed multiple target organs.
14) Swapan Paul, R.Ph.: Ultrastrcutural changes during NSAID-induced nephrotoxicity.
15) Paula Abdul, Pharm.D.: MNS-orange-induced cardiac changes: A biochemical study.
16) Kevin Bartnik, B.S., MS., DABT- Caspase-Independent Pathways of apoptosis.
17) Dr. Nilank Shah, MD.-Effect of Nutraceuticals on Acetaminophen-induced Liver injury.
18) Dr. Elliot Yung, MD.- Comparison of Potency of Lidocaine and Chloroprocaine in Sciatic Nerve Block.
19) Preeti Patel, B.Pharm, MS., PharmD. –Role of ischemia/reperfusion injury in drug-intoxicated liver.
20) Palak Desai, Bpharm, MS. –Role of PKC during flavonoid-induced apoptotic cell death in PC12 cells.
21) Payal Patel, BPharm., MS., PharmD. –Role antioxidants on various target organ genomes.
22) Vishal Javia, BPharm., MS. –Role of antioxidant combinations on genomic integrity of target organs.
23) Sharvani Chamrathi, BPharm, MS. –Role of apoptotic cell death during ischemia-reperfusion injury.
24) Hiren Panchal, BPharm, MS. –Role flavonoids during MPTP-induced neuronal cell death.
25) Dr. Sameer Munchala, MBBS, MD, MS. –Neuroprotective effect of pentoxyfylline on neuronal cell death.
26) Srinivas Kommjusyula, BPharm, MS – Drug-induced DNA damage and DNA repair pathways in kidneys.
27) Dwiti Pandya, BPharm, MS – Drug-induced Free radical responsive signaling pathways in the liver.
28) Rutesh Vyas, BPharm, MS –RT-PCR and DNA microarray analysis of drug-exposed yeast cells.
29) Manish Makhija, BPharm, MS – Drug-induced changes in electrophoretic patterns of nuclear proteins.
30) Sanjay Dholakia, BPharm, MS – PKC and apoptosis in PC12 cells.
31) Kavya Somapalli, BPharm, MS – Biochemical changes in the liver upon hypoglycemia and hyperglycemia.
32) Sweta Vyas, BPharm, MS- Pathological changes in the liver and kidneys during hypo- and hyperglycemia.
33) Ankita Kumar, MD, MS – Antioxidant responsive element (ARE) and oxidative stress in the lung.
34) Jinitaben Patel, BPharm, MS – Biochemical changes in the kidneys upon hypoglycemia and hyperglycemia.
Summer High school Interns:
1. Ms. Paula Bu-Stuyvesant HS, Intel Semifinalist: Worked on anti-toxic properties of Ocimum sanctum leaf extract] http://stuyspec.com/features/558/11-stuyvesant-students-are-named-intel-finalists-and-semifinalists-at-four-stuyvesant-has-most-finalists-in-nation/ B. S. (Harvard University); Pursuing MD/PhD
2. Mr. Anup Wattamwar, MD 2001; (Rush University Medical School): Worked on Furosemide-induced DNA fragmentation in the liver.