PRESENTATIONS AT NATIONAL AND INTERNATIONAL MEETINGS
(Invited speaker, Symposium speaker, Podium and Poster Presentations)
Ford Christina, Suhali-Amacher Natalia, Bazzi Ahmad, Ray SD.Three Weeks Exposure To Dimethylnitrosamine (dmn) – Induces Rare Forms Of Spleen And Duodenal Cancers. The Toxicologist, Presented at the 2018 SOT meeting held at San Antonio Conv Ctr, TX , March 11-15, 2018.
Gray JP, Gray, Curran CP, Fitsanakis VA, Ray SD, Stine KE and Eidemiller B.Foundational Concepts in Undergraduate Toxicology – Applying Vision & Change to the Development of Core Concepts and Learning Objectives for an Undergraduate Toxicology Course. The Toxicologist, Presented at the 2018 SOT meeting held at San Antonio Conv Ctr, TX , March 11-15, 2018.
Ray SD, Swanson KN, Reynolds KR, Pavon DM. Dietary Exposure To An Admixture Of Polyphenolics Significantly Reduces Dimethylnitrosamine (dmn) – Induced Carcinogenic Changes In Mouse Lungs. The Toxicologist (meeting supplement) 138(1): Pp. 336 (#2411).
Ray SD, Keshishyan S, Rizkalla M, Tran T. Nuclear and Mitochondrial Ultrastructural Changes During Acetaminophen (AAP) and Dimethylnitrosamine (DMN)-induced Liver Injury. American Journal of Pharmaceutical Education 2016; 80 (5) Article S2, Pp. 16.
Patel, Ami*, Lawana, V**. and Ray, SD. Pro- and Antiapoptotic Gene Expression Patterns Correlate with Histopathological Changes in the Liver and Kidneys of Mice Exposed to High Doses of Aliphatic Alcohols. Toxicol. Sciences, 144(1): Pp.122, 2015 (#663). (The Toxicologist meeting supplement) [*Ms. Patel is at Cold Spring Harbor Labs, **Mr. Lawana is at Iowa State Univ]
Earhart, JE and Ray, SD. Most bioactivation-dependent nephrotoxins induce apoptotic death alongwith unique patho-morphological characteristics in mouse kidenys. Toxicol. Sciences, The Toxicologist (meeting supplement) 138(1): Pp. 75 (#297).
Gray, JP., Billack, B., Borland, MG., Ford, SM., Gallo, M., Hall, G., Ray, SD. Et. al. The journal of toxicological education (JTOXED) – a milestone in toxicology education. Toxicol. Sciences, (The Toxicologist meeting supplement) 138(1): Pp. 437 (#1679).
Patel Priyanka, Kiersma M and Ray, SD. Apoptogenic, necrogenic and unique patho-morphological changes induced by bio-activation-dependent hepatotoxins. Presented at the 2013 SOT meetings; The Toxicological Scs (The Toxicologist meeting supplement) 132(1): 232 (#1088).
Ray, SD. and M. Parmar. A complex mixture of phytochemicals attenuate streptozotocin (STZ)-induced hyperglycemic oxidative stress and modulate pro- and anti-apoptotic gene expression in the mouse liver in vivo. NHPRS: Natural Health Products Res., International Conference held at César’s Palace, Windsor, Ontario, Canada, Podium Presentation, May 2013
Patel Ami, Lawana, Vivek and Ray, SD. Aliphatic alcohols may produce nephrotoxicity via oxidative stress(os) and influence SIRT1 and FOXO3a expression in vivo. The Toxicological Scs (The Toxicologist meeting supplement) 126(1): 256 (#1190).
Lawana, Vivek, Patel, Ami and Ray, SD. Aliphatic alcohols propagate oxidative stress-responsive cell death signals in the mouse liver and kidneys by perturbing expression of pro- and antiapoptotic genes. FASEB J, Sec. Mechanisms of Toxicity, Pp. 344 (Abst# B-139, 1050.11). http://www.fasebj.org/cgi/content/meeting_abstract/26/1_MeetingAbstracts/1050.11
Lawana VJ, Patel AB, DeBisschop M, Beckett RD and Ray SD. Aliphatic Alcohols Induce Hepato- and Nephrotoxicity In Vivo Primarily via Lipid Peroxidation and Genomic Instability. Poster Session-II, Biological Scs, Abst# 17, AACP Annual meeting abstract- 2012.
Darji, S., Guirguis, A., Ray, SD. Effectiveness of Ginger on Intraoperative and Postoperative Nausea and Vomiting in Elective Cesarean Section Patients. Am. Assoc. Pharmaceutical Scientists Annual Meeting Poster, 2011.
*Pravasi, S., Desai, S. and Ray, SD. Ethanol(EtOH) exposure in vivo potentiates diclofenac(DCLF)-induced nephrotoxicity by destabilizing genomic integrity and pro- and antiapoptotic genes. The Toxicological Scs (The Toxicologist meeting supplement) 120(2): 165 (#766). [*Society of Toxicology’s national Graduate student travel award winner]
Wexler, P., Eidelmiller, B. and Ray, SD. Toxlearn: An NLM-SOT educational collaboration. The Toxicologist, 2011.
*Desai, S., Pravasi, S., and Ray, SD. Nrf2 is the master operator which regulates the expression of pro- and anti-apoptotic genes during ethanol (EtOH)-potentiated diclofenac (DCLF)-induced hepato- and nephrotoxicity in vivo. The FASEB J, 2011. [*ASPET’s best poster award competition] http://www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/1087.10
Ray, SD. Pravasi, S. and Desai, S. The degree of oxidative stress induced by bioactivation-dependent hepatotoxins presage the mediation of caspase-activated DNAse (CAD)-dependent DNA fragmentation and Cyt c release to propel apoptotic and necrotic cell deaths in the liver in vivo. Free Rad. Boil. Med., 2010.
Ray SD. Most Hepatorenal Toxins Consistently Produce Caspase-activated DNAse (CAD)-dependent DNA Ladders and Induce Apoptosis in Vivo. Presented at the AACP Annual meeting held at Seattle, July 2010.
*Lahoti, T. and Ray, SD. Acute doxorubicin (DXR)-induced nephrotoxicity involves massive oxidative stress and an organized perturbation of mitochondria-centric pro- and anti-apoptotic genes. The Toxicologist, (SOT meeting 2010). [*SOT’s multiple Award winner]
*Shah, K, Parmar, M. and Ray, SD. ROS-mediated oxidative stress influence anti-apoptotic genes and Cyt c release in hyperglycemic mouse kidneys to initiate late nephropathic complications. Free Rad. Biol. Med., 2009.[*Best poster competition]
Kohodos, I. and Ray, S. D. Exposure to a proanthocyanidin mixture signficantly reduces dimethylnitrosamine (DMN)-Induced nephrocarcinogenesis in vivo. The Toxicologist [In Press, Presented at the SOT meeting, Baltimore, MD]
*Bhatt S, Patel C and Ray SD. Differential Expression of Pro-Apoptotic and Anti-Apoptotic Genes During Diclofenac-Induced Oxidative Stress-Mediated Nephrotoxicity In Vivo. FASEB Journal, 22:917.9, 2008. [Best Poster competition:Presented at the Experimental Biology meetings, San Diego, CA]
Parekh J, Sengupta A, and Ray SD. Effects of Structurally and Functionally Diverse Group of Phytochemicals on Aniline Hydroxylation (CYP2E1) of Control and Acetone-Induced Rat Liver Microsomes. FASEB Journal, Vol. 22: 1137.3, 2008. [Presented at the Experimental Biol. meetings, San Diego, CA]
*Patel C, Bhatt S, and Ray SD. Differential Expression Of Pro- and Antiapoptotic Genes Under the Influence Of Oxidative Stress During CCl4-Medaited Liver Injury in Mice. FASEB Journal, Vol. 22: 1140.3, 2008. [*Best poster competition: Presented at the Experimental Biol. meetings, San Diego, CA]
Parmar M, Imail S and Ray SD. A Triple Bioflavonoid Mixture Modulates Pro- and Anti-Apoptotic Gene Expression During Streptozocin (STZ)-Induced Oxidative Stress in the Mouse Liver. The Toxicologist, Vol 97(1): (Abst#769), 2008. [Soc. of Toxicology meetings, Seattle, WA]
Ray, S. D., Bulku, E., Zinkovsky, D., Parmar, M., Zinkovsky, D., Syed, I., Patel, C., Bhatt, S., Hackman, R. M. and Stohs, S. J. Dietary supplement Thermoplus® reduces the level of oxidative stress and stabilizes the genomic integrity in the liver and kidneys of Fisher 344 rats. Journal of the American Coll. of Nutrition (In Press, 2007).
Bulku, E., Rathod, J., Ismail, S., Parmar, M. and Ray, S. D. Antiapoptotic and Antinecrotic Properties of Bioflavonoids Curcumin and Rutin. Am. J. of Pharma. Edu. 71 (3) Article 60, 2007. [AACP Annual meeting held in Orlando, FL]
*Rathod, J., Ismail, S., Parmar, M. and Ray, S. D. Modulation of matrix metallo proteases (MMPs) and MDM2 during acute dimethylnitrosamine (DMN)-induced nephrotoxicity in mice. The FASEB Journal. 21:730.2, 2007. [*Exptl. Biology 2007 meeting held at the Washington DC; Selected to participate at the ASPET’s best poster award competition]
Ismail, S., Rathod, J., Parmar, M. and Ray, S. D. Modulation of expression of matrix metallo proteinases (MMPs -9, -10, & -12) during dimetyl nitrosamine (DMN)-induced liver cell death. Society of Toxicology meetings, Charlotte, NC, The toxicologist, Vol 96(1): 158 (Abst#769), 2007. [Society of Toxicology meetings, Charlotte, NC]
Ray, S. D., Parmar, M., Zinkovsky, D., Syed, I., Rathod, J., Shah, K., Hackman, R. M. and Stohs, S. J. Eight weeks exposure effects of a novel dietary supplement- thermoplus on serum biochemistry and histopathology of vital target organs of fisher rats. The Toxicologist, Vol 96(1): 298 (Abst#1442), 2007 [Society of Toxicology meetings, Charlotte, NC]
S. D. Ray. “How Antitoxic and Anticancer signals Maneuver Programmed and Unprogrammed Cell Death In Vivo? Proceedings of the Apoptosis Congress, Editor: Marc Diderich, Luxembourg, 2006.
S. D. Ray, N. Patel, N. Shah, A. Nagori, A. Nqvi, and S. J. Stohs. Long-term exposure effects of a novel phytochemical-nutraceutical mixture (metabolic nutrition system-platinum) on serum biochemistry and histopathology of seven vital target organs of B6C3F1 mice. The Toxicologist, Vol. 90, Abst# 497, 2006. [Society of Toxicology meetings, San Diego, CA].
*N. Patel and S. D. Ray. Silymarin pre-exposure modulates oxidative stress and bcl-xl expression in the liver and prevents doxorubicin-induced apoptotic and necrotic cell deaths. The Toxicologist, Vol. 90, Abst# 1979, 2006. [Society of Toxicology meetings, San Diego, CA]. [*Gordon Research Conference Graduate student award]
*E. Bulku, D. Zinkovsky, N. Patel and S. D. Ray. Curcumin pre-exposure in vivo prevents acetaminophen-induced apoptotic and necrotic cell deaths in the liver. FASEB JOURNAL 20 (5): A1144-A1144, Part 2, Mar 7, 2006. [Experimental Biology meetings, San Francisco, CA]
[* National press release by FASEB- Interview by ‘The Scientist’]
Elida Bulku, Jasmine Rathod, Ismail Syed, Daniel Zinkovsky, and S. D. Ray. Exposure to curcumin and citrus bioflavonoids prevent acetaminophen-induced programmed and unprogrammed cell deaths in the liver. Proceedings of the Gordon Research Conference, Meeting held at the Bryant University, Smithfield, VT; July 31st thru August 4, 2006.
Ray, S. D., S. Stohs and G. B.. Corcoran. Activation of endonuclease, or caspase-activated DNAse (CAD), as a marker of apoptosis rather than necrosis in drug- or chemical-induced oncosis in vivo. The Toxicologist, Vol. 64, Abst# 2301, 2005.
Ray, S. D., A. Nagori; A. Naqvi; N. Shah, N. Patel and S. Stohs. Four week exposure to a novel nutritional mixture containing a series of polyphenolic phytochemicals antagonizes acetaminophen-induced hepatotoxicity in vivo. The Toxicologist, Vol. 64, Abst# 1410, 2005.
Ray, S. D., Hackman, Rm. And Stohs, S. J. Exposure to an ephedra and caffeine containing metabolic nutrition system for 8 months does not alter organ histopathology or serum chemistry of B6C3F1 mice. Proc. American Coll. Of Nutrition meeting, Nashville, TN, 2003.
*Patel, C. P., Raje, R. and Ray, S. D. Acute ethanol pre-exposure sensitizes liver and kidneys to furosemide-induced apoptotic and necrotic cell deaths by selectively influencing oxidative stress and genomic DNA fragmentation in vivo. The Toxicologist Vol. 73, S-1, 2004. [* National Graduate Student Award winner]
*Phadke, S., Patel, C. and Ray, S. D. Liver cell death after acetaminophen (AP) overdose: apoptosis or oncotic necrosis? Toxicological Sciences Vol. 73, S-1, 2004. [* National Graduate Student Award winner]
Ray, S. D., R. Hackman and S. Stohs. Exposure for one year to a metabolic nutrition system containing ephedra and caffeine does not alter serum chemistry profile or target organ histopathology of B6C3F1 mice. Toxicological Sciences Vol. 73, S-1, 2004.
Ray, SD. Antitoxic properties of polyphenolic phytochemicals in vivo. Symposium Speaker, Worldnutra Congress, San Francisco, CA. Proc. Of Worldnutra Congress, 2004.
Ray S. D. Molecular regulation of antiapoptotic and antinecrotic pathways by citrus bioflavonoids. AMERICAN CHEMICAL SOCIETY 228: U71-U71 132-AGFD, Part 1, AUG 22, 2004.
Ray, S. D. Drug and Chemically Induced Free Radical-Mediated Patterns of Target Organ Cell Death In Vivo. Proc. Soc. of Free Radical Research, Seoul, South Korea, 2003.
[*INVITED SYMPOSIUM PRESENTATION at Seoul, South Korea]
Ray, S. D. Oxidative stress is the master operator of drug and chemically-induced programmed and unprogrammed cell death: Implications of natural antioxidants in vivo. International Congress on Food factors, Tokyo, 2003. [*INVITED SYMPOSIUM PRESENTATION]
Ray, S. D. Oxidative stress orchestrates both apoptosis & necrosis in vivo: A new perspective from molecular toxicology. Free Rad. Res. Vol. 37, (suppl.), pp. 29, 2003.
[*INVITED SYMPOSIUM PRESENTATION at Ionina, Greece]
Ray, S. D., S. Gross, *A. Chou, *C. Brucculeri, D. Bagchi and S. Stohs. Mechanisms of Cell Death after Acetaminophen overdose: Apoptosis or Oncotic Necrosis? Experimental Biology-2003; Late Breaking Abst. session, San Diego, CA. [*Merck Travel Award winners]
*S. Phadke; R. Raje; Ray, S. D. Acute ethanol (EtOH) exposure in vivo potentiates acetaminophen (AAP)-induced hepatocellular apoptosis by modulating oxidative stress and expression of bcl-XL and p53 genes in the liver. The Toxicologist 72(1): 361 (#1752), 2003. [SOT National award winner].
Stohs, S., Gross, S., Patel, C., Hackman, R. and Ray, S. D. In vivo exposure to an ephedra containing metabolic nutrition system does not alter serum biochemistry and histopathology of seven vital target organs of B6C3F1 mice.
The Toxicologist 72(1): 255 (#1243), 2003.
*Rotollo, J. A. and Ray, S. D. Streptozotocin (STZ)-induced hyperglycemia differentially modulates acetaminophen (AAP)-induced hepatic expression of cytokine levels and apoptotic cell death. Toxicological Scs. 60(1): 377, 2002. [SOT National award winner].
Ray, S. D. et al. Reversal of acetaminophen (AAP) and thioacetamide (TAM)-induced Caspase-Activated DNAse (CAD) and oxidative stress-mediated apoptotic and necrotic liver cell deaths by momordica charantia bioflavonoids.
Toxicological Scs. 60(1): 377, 2002.
Ray, S. D., Lee, H. Y., Khantsis, I., Markovics, E., Phadke, S., Mohammad, S. and R. R. Raje. Alloxan and streptozotocin-induced diabetes potentiates furosemide-induced liver-injury and liver cell apoptosis in vivo.
Toxicological Scs. 60(1): 377, 2001.
Ray, S. D., Parikh, H., Ali, S. and Bagchi, D. IH636 Grape Seed Proanthocyanidin Extract (GSPE) exposure significantly attenuates dimethylnitrosamine-induced liver cancer and mortality in ICR mice. Proc. Am. Assoc. Can. Res. 41(1): 460 (#2928), 2000. [H.Parikh received Award; InterHealth National Press Release]
Ray, S.D., Balasubramanian, G., Raje, R. R., Reid, V. E., Reddy, C.S. and Bagchi, D. Doxorubicin-induced hepatotoxicity may involve apoptotic cell death by modulating expression of bcl-XL and p53. Toxicological Scs. 4(1):100 (#530), 2000. [G. Bala received SOT National Travel Award]
Parikh, H., Bagchi, D. and Ray, S.D. Effects of long term chronic exposure of IH636 novel grape seed proanthocyanidin extract (GSPE) on multiple target organs in mice. The FASEB J. 14(8): A1560, 2000.
Bagchi, D., Hickey, E., Parikh, H. and Ray, S.D. In Vivo IH636 Grape Seed Proanthocyanidin Extract (GSPE) exposure inhibits mouse liver microsomal CYP4502E1-dependent aniline hydroxylation in vitro. Toxicological Scs. 4(1):100 (#468), 2000.
*Hickey, E. J., Reid, V. E., Raje, R. R. and Ray, S.D. Diclofenac-induced nephrotoxicity may involve oxidative stress and massive genomic DNA fragmentation in vivo. Toxicological Scs. 4(1):118 (#556), 2000. [*Hickey received SOT National Travel Award; Long Island University Press Release]
Raje, R. R., Hickey, E. J., Reid, V. E. and Ray, S.D. Salicylic acid and chloroform-induced nephrotoxicities may involve genomic DNA fragmentation and cell death by apoptosis. Toxicological Scs. 4(1):118 (#556), 2000.
Ray, S.D., Hickey, E. and Bagchi, D. A novel Grape Seed Proanthocyanidin Extract (GSPE) protects multiple target organ toxicities induced by amiodarone (Lung), dimethylnitrosamine (Spleen), CdCl2 (Kidney) and MOCAP (Brain). FASEB J. 13(4): A187, 2000.
Hickey, E., Parikh, H., Bagchi, D. and Ray, S.D. IH636 Grape Seed Proanthocyanidin Extract inhibits cytochrome P450-IIE1 dependent aniline hydroxylation in induced and uninduced rat liver microsomes. J. Am. Coll. Nutr. 18(5): 533 (#50), 1999.
Ray, S. D., Balasubramanian, G., Khander, A., Reddy, C. and Bagchi, D. Poly (ADP-Ribose) polymerase modulators 4-aminobenzamide (AB) and nicotinamide (NICO) protect against acetaminophen (AAP)-induced hepatotoxicity in mice by influencing expression of bcl-XL and p53. Toxicological Scs. 48(1S): 91 (#425), 1999.
*Wong, V., Fu, K., Kohanchi, B., Bagchi, D and Ray, S. D. Antioxidant grape seed extract (GSPE) and a DNA repair modulator 3-aminobenzamide (3-AB) protects doxorubicin (DOX)-induced cardiotoxicity in vivo. Toxicological Scs. 48(1S): 156 (#731), 1998. [*Received E.Merck/W.Virnia Univ. Undergrad Pharmacy award]
Ray, S. D., Patel, D., Wong, V., Fu, K., Rinkovsky, A. and Bagchi, D. Effect of a novel IH636 grape seed proanthocyanidin extract on acetaminophen-induced nephrotoxicity. 39th Annual Meeting of the American College of Nutrition [INVITED PRESENTATION], 1998.
Ray, S. D., Kumar, M. A. and Bagchi, D. In Vivo abrogation of acetaminophen-induced hepatic genomic DNA fragmentation and apoptotic cell death by a novel grape seed proanthocyanidin extract GSPE. The FASEB J. 12(5), Pp. A779 #4516, 1998. [*Above minisymposium presentation was chosen by FASEB National Program Committee for Press release]
Ray, S. D. Modulation of expression of Bcl-2, Bcl-XL and Bcl-XS during acetaminophen induced hepatocellular apoptosis, 1998. Toxicological Scs. 42 (1S), Pp.190.
*Strika, S.1, *Dobrogowska, A2, Khander, A. and Ray, S. D. Furosemide induces apoptosis in the liver and kidneys in vivo. The Toxicological Scs. 42(1S), Pp 357, 1997. [*E.Merck/W.Virnia Univ. Undergrad Pharmacy student award winner]
Ray, S. D. Does ethanol potentiate acetaminophen-induced hepatocellular apoptosis? Fund. Appl. Toxicol. 36 (1), Pp. 247, 1997.
Manolas, T., Wattamwar, A. and Ray, S. D. Induction of hepatocellular apoptosis by various alcohols in normal and Spontaneously Hypertensive-Stroke Prone rats. Fund. Appl. Toxicol. (The Toxicologist) 36 (1), Pp. 247, 1997. [T. Manolas- E.Merck/W.Virginia Univ. Undergrad Pharmacy award winner]
Ray, S. D., Munoz, R., and Kraner, J. C. 3-Aminobenzamide, a modulator of apoptosis and necrosis induced by acetaminophen does not interfere woth p450IIE1 activity in vivo or in vitro. Fund. Appl. Toxicol. 30 (1), Pp. 71, 1996.
Dhruva, D., Sharma, S., Shleyfer, L., Raje, R. R. and Ray, S. D. Acetaminophen induced hepatocellular apoptosis in vivo: Role of Ca2+ -activated nitric oxide pathway in the absence of bcl-2 expression. Fund. Appl. Toxicol. 30 (1), Pp. 165, 1996. [Dhruva : SOT National Travel Award winner]
*Dhruva, D. and Ray, S. D. Role of nitric oxide in acetaminophen-induced apoptosis and necrosis and its modulation by 3-aminobenzamide. J. Clinical Toxicology 34(5), Pp 575, 1996. [*Above work received American Academy of Clinical Toxicol. National Res. Award]
Tran, M., Stohs, S., Newton, S., Bagchi, D., Tang, L. and Ray, S. D. Cadmium and chromium induced oxidative stress and programmed cell death in cultured J774A.1 macrophage cells. Fund. Appl. Toxicol. 30 (1), Pp. 167, 1995.
Ray, S. D. and R. R. Raje. Acetaminophen-induced hepatocellular apoptosis in vivo shows signs of loss of mitochondrial volume regulation. Fund. Appl. Toxicol. (The Toxicologist) 15 (1): Pp. 133, 1995.
*Yahya, S. M., Ray, S. D., and Raje, R. R. Abrogation of acetaminophen induced hepato- and nephrotoxicity by 3-aminobenzamide, A DNA repair modulator. Fund. Appl. Toxicol. (The Toxicologist) 15 (1): Pp. 133, 1995. [*SOT National Travel Award winner]
Ray, S. D., Mumaw, V.R., Lippman, R., Fraiss, M.W. Acetaminophen-induced apoptosis and necrosis: In Vivo protection by cholesteryl hemisuccinate pretreatment. The Toxicologist 15 (1), Pp. 187, 1994.
Mumaw, V.R., Ray, S.D., and Corcoran, G.B. Dimethylnitrosamine-induced DNA fragmentation and toxicity in mouse liver, spleen, and kidney. The Toxicologist 14 (1), Pp. 298, 1994.
Fariss, M.W., Lippman, H.R., Ray, S.D., and Smith, J.D. Characterization of cholesteryl hemisuccinate protection against CCl4-induced hepatotoxicity. The Toxicologist 14 (1), Pp. 329, 1994.
Corcoran, G.B., Yorkin, R.D. and Ray, S.D. Calmodulin and calcium channel antagonists inhibit acetaminophen-induced DNA fragmentation and hepatotoxicity in mice. The Toxicologist 12(1): 131, 1992.
Burchiel, S.W., Davis, D.P., Ray, S.D., Barton, S. and Corcoran, G.B. Induction of apoptosis-like cell death by 7,12-Dimethylbenz(A)anthracene (DMBA) in the A20.1 murine B- lymphoma cell line. The Toxicologist 12(1): 341, 1992.
Ray, S.D., Kamendulis, L., Shen, W., Corcoran, G.B. Acetaminophen-induced DNA fragmentation and cell death studied in vitro in cultured mouse hepatocytes. The Toxicologist 11(1): 67, 1991.
46. Corcoran, G.B., Ray, S.D., Sorge, C.L. and Kamendulis. DNA fragmentatio and increase in nuclear Ca2+ precede dimethylnitrosamine induced hepatic necrosis in mice. The Toxicologist 11(1): 102, 1991.
Kamendulis, L., Shen, W., Ray, S.D. and Corcoran, G.B. DNA fragmentation precedes (CH3)2nitrosamine cytotoxicity in cultured mouse hepatocytes. The Toxicologist 11(1): 254, 1991. [*Above work received SOT National ward]
Burchiel, S.W., Davis, D., Ray, S.D. Thilstead, J.P. and Corcoran, G.B. DNA fragmentation and cell death induced by DMBA in lymphoid and non lymphoid organs of B6C3F1 mice. The Toxicologist 11(1): 269, 1991.
Corcoran, G.B., Ray, S.D., Kamendulis, L., and Kazemi, S. Effects of Ca2+-endonuclease and DNA repair inhibitors on hepatic necrosis induced by dimethylnitrosamine. FASEB J. 5: A1563, 1990.
Kraner, J., Lasker, J., Ray, S.D., Mouck, M. and Raucy, J.L. Induction of P450IIE1 by acetone in culture rabbit hepatocytes involves increased protein synthesis. FASEB J. 5: 6635, A1515. 1990.
Ray, S.D., Cai, Z. and Mehendale, H.M. Paradoxical toxicity of CCl4 in isolated hepatocytes from chlordecone, phenobarbital and mirex pretreated rats. The Toxicologist 10(1): 53, 1990.
Corcoran, G.B., Ray, S.D., Sorge, C.L., Braun, E., Tavacoli, A. and Raucy, J.L. Nuclear Ca2+ accumulation and massive DNA fragmentation precede acetaminophen-induced liver-injury in mice. The Toxicologist 10(1): 294, 1990.
Ji, S., Ray, S.D., Jung, K.H. and Boyaesky, A.B. The isolated perfused rat liver as an experimental model for vascular toxicity. Toxicologist 10(1): 60, 1990.
Kraner, J., Corcoran, G.B., Ray, S.D., Lasker, J. and Raucy, J.L. P450IIE1 Enzyme expression in isolated and cultured hepatocytes. The Toxicologist 10(1): 126, 1990. [*This work received Molecular Biology Specialty Section award]
*Ray, S. D. and Mehendale, H.M. Suppression of cell division by carbon tetrachloride in Reuber hepatoma cells pre-exposed to chlordecone. The Toxicologist 9: 68, 1989. [*This work was chosen by the SOT Program Committee for Discussion session]
*Ray, S. D. and Mehendale, H.M. Potentiation of carbon tetrachloride hepatotoxicity and lethality by various alcohols. The Toxicologist 9(1): 59, 1989. [*Above work was chosen by the SOT Prog. Com. for Discussion session]
Ray, S. D. and Mehendale, H.M. Influence of phenobarbitol, mirex and chlordecone on the effect of carbon tetrachloride on Reuber hepatoma cell growth. FASEB J. 2(4)1989.
Ray, S. D., Esterline, RL and Ji, S. Cytrochrome P450-independent mechanism of alchol-poteniated acetaminophen hepatotoxicity. The Toxicologist. 8 (1) 130. 1988.
Ray, S. D., Esterline, R. L. and Ji, S. Reversible and Irreversible components of acetaminophen-induced “Slow Inhibition of hepatic respiration” in livers from rats acutely pretreated with ethanol. FASEB J 2(4): 802, 1988.
Ji, S., Ray, S. D., Esterline, R. L. and Laskin, D. “Endocrinoimmunotoxicology ” of acetaminophen. FASEB J 2(6): A1680, 1988.
Ray, S. D., Lee, P. Y. and Ji, S. Modulation of acetaminophen Hepatotoxicity in rats by endocrine status.The Toxicologist 7(1): 137, 1987.
Ji, S., Ray, S. D., Pilaro, A. and Laskin, D. Evidence for polymorphonuclear leukocyte involvement in acetaminophen hepatotoxicity. Toxicologist 6(1) ,187. 1986.
Ray, S. D. and Ji, S. Hypophysis-mediated effects of alcohol on peroxidase activity of rat liver and ovaries. The Toxicologist 6 (1 ),187, 1986.
Ray, S. D., *Esterline, R.L. and Ji, S. Inhibition of acetaminophen-induced liver injury by glucose mannitol or ethanol: Evidence that glucose is an endogenous free radical scavenger. Fed. Proc. 45 (3) : 702, 1986. [*Travel award winner]
Laskin, D., Ray, S. D., Pilaro A. and Ji, S. Hypophysis and Granulocyte involvement in alcohol potentiation of acetaminophen hepatotoxicity. Fed. Proc. 45 (3): 701, 1986.
Ray, S. D. and Ji, S. Extracellular Ca2+-dependent and independent mechanisms of acetaminophen hepatotoxicity. The Toxicologist 6 (1 ),187, 1986.
Ray, S.D. and Ji, S. Differential action of ethanol and acetaminophen in inducing cell injury: A biochemical study. Fed. Proc. 44 (5) :1485, 1985.